Publications

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Regeneration of the epidermal barrier in irritant hand eczema: in vivo evaluation of the efficacy of a therapeutic basic preparation.

C. Skudlik, D. Westphal, K. Kipper und W. Wigger-Alberti. Dermatologie in Beruf und Umwelt, Jahrgang 71, Nr. ●/2023, S. 1-8

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Efficacy of barrier-regenerating effects of topicals after irritant contact dermatitis: Results of a skin bioengineering study

Elsner P, Westphal D, Devillechabrolle E, Demessant AL, Wigger-Alberti W
Dermatologie in Beruf und Umwelt, Jahrgang 70, Nr. 4/2022, S. 179-190

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A phase I, randomized, double-blind study to assess the safety, tolerability, and efficacy of the topical RORC2 inverse agonist PF-06763809 in participants with mild-to-moderate plaque psoriasis

Berstein G, Zhang Y, Berger Z, Kieras E, Li G, Samuel A, Yeoh T, Dowty H, Beaumont K, Wigger-Alberti W, von Mackensen Y, Kroencke U, Hamscho R, Garcet S, Krueger JG, Banfield C, Oemar B
Clin Exp Dermatol. 2021 Jan; 46 (1): 122–129

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Evaluation of BepanGel Hydrogel Efficacy and Tolerability Using an Abrasive Wound Model in a Within-Person, Single-Center, Randomized, Investigator-Blind Clinical Investigation

Lei Zhang, Raffaella de Salvo, Sonja Trapp, Walter Wigger-Alberti, Ragna Williams, Lucie Delcour, Bart Rossel, Maarten T. Huisman
Dermatol Ther (Heidelb) 2020 Oct; 10(5):1075-1088. doi:10.1007/s13555-020-00432-5; Epub 2020 Aug 2

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Rehabilitation and Prevention of Hand Eczema

Wulfhorst B, Strunk M, Skudlik C, Heichel T, Sonsmann F, Wilke A, Wigger-Alberti W, John SM
In: Johansen J., Mahler V., Lepoittevin JP., Frosch P. (eds) Contact Dermatitis. (2020) pp 1-48, Springer, Cham

Adapting epicutaneous patch testing protocols to assess immediate-type skin reactions

Mehling A, Benard S, Braun N, Degwert J, Duttine M, Jassoy C, Merk H, Rossow U, Welzel J, Wigger-Alberti W, Wilhelm KP, Ennen J
Int J Cosmet Sci. 2020:(42):328-335

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Comparison of Skin Structural and Functional Parameters in Well-Nourished and Moderately Undernourished Infants

Hughes-Formella B, Wunderlich O, Williams R, Fernández J, Kim YZ, Wigger-Alberti W, Pecquet S, Moodycliffe A
Skin Pharmacol Physiol. 2019;32:212-223

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Wound healing characteristics of a novel wound healing ointment in an abrasive wound model: A randomised, intra-individual clinical investigation

Kuhlmann M, Krause-Kyora F, Ebbinghaus M, Williams R, Wolber R, Wigger-Alberti W, von Mackensen YL
Wound Medicine 2019 March;24(1):24-32

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Efficacy and safety of a new 5% minoxidil formulation in male androgenetic alopecia: A randomized, placebo-controlled, double-blind, noninferiority study

Blume-Peytavi U, Issiakhem Z, Gautier S, Kottner J, Wigger-Alberti W, Fischer T, Hoffmann R, Tonner F, Bouroubi A, Voisard JJ
J Cosmet Dermatol. 2019 Feb;18(1):215-220

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A Phase I Randomized Controlled Trial to Evaluate Safety and Clinical Effect of Topically Applied GSK2981278 Ointment in a Psoriasis Plaque Test

Kang EG, Wu S, Gupta A, von Mackensen YL, Siemetzki H, Freudenberg JM, Wigger-Alberti W, Yamaguchi Y.
Br J Dermatol. 2018 Jun;178(6):1427-1429

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Dermocosmetics for Use in Rosacea: Guideline of the Society for Dermopharmacy

Kresken J, Kindl U, Wigger-Alberti W, Clanner-Engelshofen BM, Reinholz M
Skin Pharmacol Physiol. 2018 Mar 29;31(3):147-154

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Comparison of Occlusive and Open Application in a Psoriasis Plaque Test Design. Exemplarily Using Investigations of Mapracorat 0.1% Ointment versus Vehicle and Reference Drugs

Wigger-Alberti W, Williams R, von Mackensen YL, Hoffman-Wecker M, Grossmann U, Staedler G, Nkulikiyinka R, Shakery K.
Skin Pharmacol Physiol. 2017;30(2): 102-114

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Clinical trial shows lasting function of a new moisturizing cream against vaginal dryness

Henneike-von Zepelin HH, Williams R, Havemeister W, Wigger-Alberti W, Nolte KU
Wien Med Wochenschr. 2017 May;167(7-8): 189-195

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Confocal Raman microscopy and multivariate statistical analysis for determination of different penetration abilities of caffeine and propylene glycol applied simultaneously in a mixture on porcine skin ex vivo

Mujica Ascencio S, Choe C, Meinke MC, Müller RH, Maksimov GV, Wigger-Alberti W, Lademann J, Darvin ME
Eur J Pharm Biopharm. 2016 Jul;104:51-8

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A phase I randomized trial to assess the effect on skin infiltrate thickness and tolerability of topical phosphodiesterase inhibitors in the treatment of psoriasis vulgaris using a modified psoriasis plaque test

Snape SD, Wigger-Alberti W, Goehring UM
Br J Dermatol. 2016 Sep;175(3):479-86

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Cumulative irritation, sensitizing potential, phototoxicity and photoallergy of ozenoxacin in healthy adult volunteers

Gropper S, Cepero AL, Dosik JS, LaStella KP, Siemetzki H, Wigger-Alberti W
Future Microbiol. 2014;9(8 Suppl):S23-31

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Fußpflege bei Diabetes: Adäquate Pflege trockener und empfindlicher Haut am diabetischen Fuß (Foot care in diabetes: Adequate care of dry and sensitive skin for diabetic foot)

Wigger-Alberti, W, Williams R, Neubourg T, Hanisch E, Schulte-Walter J
Kosmetische Medizin 1.15; 30-35

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Digital Imaging for measuring of hair growth on the human scalp

Hoffmann R, Lüdtke H, Hoffman-Wecker M, Hughes-Formella BJ
Berardesca E. et al. (eds); Non Invasive Diagnostic Techniques in Clinical Dermatology (2014): 413-422

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Efficacy of a tyrothricin-containing wound gel in an abrasive wound model for superficial wounds

Wigger-Alberti W, Stauss-Grabo M, Grigo K, Atiye S, Williams R, Korting HC
Skin Pharmacol Physiol. 2013;26(1):52-6

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Efficacy and patient-reported outcomes of a new mometasone cream treating atopic eczema

Ruzicka T, Willers C, Wigger-Alberti W
Skin Pharmacol Physiol. 2012;25(6):305-12

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Tandem repeated irritation in aged skin induces distinct barrier perturbation and cytokine profile in vivo

Angelova-Fischer I, Becker V, Fischer TW, Zillikens D, Wigger-Alberti W, Kezic S
Br J Dermatol. 2012 Oct;167(4):787-93

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Bioavailability, antipsoriatic efficacy and tolerability of a new light cream with mometasone furoate 0.1%

Korting HC, Schöllmann C, Willers C, Wigger-Alberti W
Skin Pharmacol Physiol. 2012;25(3):133-41

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Comparison of the spread of three botulinum toxin type A preparations

Kerscher M, Roll S, Becker A, Wigger-Alberti W
Arch Dermatol Res. 2012 Mar;304(2):155-61. Epub 2011 Oct 15

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Interlaboratory studies with a proposed patch test design to evaluate the irritation potential of surfactants

Mehling A, Chkarnat C, Degwert J, Ennen J, Fink E, Matthies W, Roethlisberger R, Rossow U, Schnitker J, Tronnier H, Wigger-Alberti W, Wilhelm KP
Contact Dermatitis. 2010 Mar;62(3):157-64

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AN2728 demonstrates significant efficacy in three phase Ib psoriasis trials

Beutner K, Lathrop A, Marti D, Gassmueller J
JAAD, 2009;60:Supplement 1, 168

Validation of TrichoScan technology as a fully-automated tool for evaluation of hair growth parameters

Gassmueller J, Rowold E, Frase T, Hughes-Formella B
Eur J Dermatol. 2009 May-Jun;19(3):224-31

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Using a novel wound model to investigate the healing properties of products for superficial wounds

Wigger-Alberti W, Kuhlmann M, Ekanayake S, Wilhelm D
J Wound Care. 2009 Mar;18(3):123-28, 131

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Activity of different desoximetasone preparations compared to other topical corticosteroids in the vasoconstriction assay

Borelli C, Gassmueller J, Fluhr JW, Nietsch KH, Schinzel S, Korting HC
Skin Pharmacol Physiol. 2008;21(3):181-7

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Topical fulvestrant solution has no effect on male and postmenopausal female androgenetic alopecia: results from two randomized, proof-of-concept studies

Gassmueller J, Hoffmann R, Webster A
Br J Dermatol. 2008 Jan;158(1):109-15

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Assessment of topical corticosteroid activity using the vasoconstriction assay in healthy volunteers

Görne RC, Greif C, Metzner U, Wigger-Alberti W, Elsner P
Skin Pharmacol Physiol. 2007;20(3):133-40

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Anti-inflammatory and skin-hydrating properties of a dietary supplement and topical formulations containing oligomeric proanthocyanidins

Hughes-Formella B, Wunderlich O, Williams R
Skin Pharmacol Physiol. 2007;20(1):43-9

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Induction of a hardening phenomenon by repeated application of SLS: analysis of lipid changes in the stratum corneum

Heinemann C, Paschold C, Fluhr J, Wigger-Alberti W, Schliemann-Willers S, Farwanah H, Raith K, Neubert R, Elsner P
Acta Derm Venereol. 2005;85(4):290-5

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Transepidermal water loss dynamics of human vulvar and thigh skin

Warren R, Bauer A, Greif C, Wigger-Alberti W, Jones MB, Roddy MT, Seymour JL, Hansmann MA, Elsner P
Skin Pharmacol Physiol. 2005 May-Jun;18(3):139-43

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Percutaneous penetration of topically applied melatonin in a cream and an alcoholic solution

Fischer TW, Greif C, Fluhr JW, Wigger-Alberti W, Elsner P
Skin Pharmacol Physiol. 2004 Jul-Aug;17(4):190-4

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The atrophogenic potential and dermal tolerance of calcipotriol/betamethasone dipropionate ointment compared with betamethasone dipropionate ointment

Traulsen J, Hughes-Formella BJ
Dermatology. 2003;207(2):166-72

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The tandem repeated irritation test: a new method to assess prevention of irritant combination damage to the skin

Wigger-Alberti W, Spoo J, Schliemann-Willers S, Klotz A, Elsner P
Acta Derm Venereol. 2002;82(2):94-7

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The atopy patch test -- reproducibility and comparison of different evaluation methods

Heinemann C, Schliemann-Willers S, Kelterer D, Metzner U, Kluge K, Wigger-Alberti W, Elsner P
Allergy. 2002 Jul;57(7):641-5

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Different skin thinning potential of equipotent medium-strength glucocorticoids

Korting HC, Unholzer A, Schäfer-Korting M, Tausch I, Gassmueller J, Nietsch KH
Skin Pharmacol Appl Skin Physiol. 2002 Mar-Apr;15(2):85-91

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Anti-inflammatory efficacy of topical preparations with 10% hamamelis distillate in a UV erythema test

Hughes-Formella BJ, Filbry A, Gassmueller J, Rippke F
Skin Pharmacol Appl Skin Physiol. 2002 Mar-Apr;15(2):125-32

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Tandem application of sodium lauryl sulfate and n-propanol does not lead to enhancement of cumulative skin irritation

Kappes UP, Göritz N, Wigger-Alberti W, Heinemann C, Elsner P
Acta Derm Venereol. 2001 Nov-Dec;81(6):403-5

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Treating hypertrophic scars for 12 or 24 hours with a self-adhesive hydroactive polyurethane dressing

Schmidt A, Gassmueller J, Hughes-Formella B, Bielfeldt S
J Wound Care. 2001 May;10(5):149-53

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Experimental irritant contact dermatitis due to cumulative epicutaneous exposure to sodium lauryl sulphate and toluene: single and concurrent application

Wigger-Alberti W, Krebs A, Elsner P
Br J Dermatol. 2000 Sep;143(3):551-6

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Effects of various grit-containing cleansers on skin barrier function

Wigger-Alberti W, Fischer T, Greif C, Maddern P, Elsner P
Contact Dermatitis. 1999 Sep;41(3):136-40

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Experimentally induced chronic irritant contact dermatitis to evaluate the efficacy of protective creams in vivo

Wigger-Alberti W, Caduff L, Burg G, Elsner P
J Am Acad Dermatol. 1999 Apr;40(4):590-6

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Efficacy of protective creams in a modified repeated irritation test. Methodological aspects

Wigger-Alberti W, Rougier A, Richard A, Elsner P
Acta Derm Venereol. 1998 Jul;78(4):270-3

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Anti-inflammatory effect of hamamelis lotion in a UVB erythema test

Hughes-Formella BJ, Bohnsack K, Rippke F, Benner G, Rudolph M, Tausch I, Gassmueller J
Dermatology. 1998;196(3):316-22

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Self-application of a protective cream. Pitfalls of occupational skin protection

Wigger-Alberti W, Maraffio B, Wernli M, Elsner P
Arch Dermatol. 1997 Jul;133(7):861-4

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Validation of an in vivo wound healing model for the quantification of pharmacological effects on epidermal regeneration

Lévy JJ, von Rosen J, Gassmüller J, Kleine Kuhlmann R, Lange L
Dermatology. 1995;190(2):136-41

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Comparison of the effects of calcipotriol, prednicarbate and clobetasol 17-propionate on normal skin assessed by ultrasound measurement of skin thickness

Lévy J, Gassmüller J, Schröder G, Audring H, Sönnichsen N
Skin Pharmacol. 1994;7(4):231-6

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[Imaging subcutaneous atrophy in circumscribed scleroderma with 20 MHz B-scan ultrasound]

Lévy JJ, Gassmüller J, Audring H, Brenke A, Albrecht-Nebe H
Hautarzt. 1993 Jul;44(7):446-51.

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